This is my 4th time ordering 3 bottles, so it must work!! I was running out a few weeks back and I thought I would try to go without and see if the problems came back. Within 2 weeks I was miserable!! I was exhausted again and I constantly found myself pulling at my seatbelt in my car to get it off my stomach. It is a huge blessing that the pain subsides to almost nothing while on Endovan and I realized I NEVER yank on my belt when I’m taking the pills!!