I have only been on Endovan for a week and few days. I used to have irritable bowel syndrome – it went away in pregnancy (I miscarried) – but returned when I became stressed. I tried everything to get rid of it until I finally went to a gastrointestinal doctor who ordered scans and found either a fibroid or endometriosis. I need another scan to determine for sure, but I found Endovan by accident and ordered it. I took it the first day and noticed severe pain in my left lower stomach. I ran to check my xrays which I had a copy of and saw that it is exactly where the mass was. Seems the Endovan was working on it immediately. Over the next few days I noticed less brown spotting and less back pain. I got my monthly and felt little pain but still some in lower back area and digestion issues, though they are improving slowly. I will send an update after taking Endovan for a month and report back. Thanks Endovan Team.