I have been on Endovan about a month or so. I do believe it’s helping! My stomach does not seem to protrude as much! I have not experienced any negative side effects. Now I have a couple of small ones and a large one the size of a melon, so it’s going to take a little more time to get that sucker down. I’m so glad Endovan is an option for us, because a hysterectomy is a last resort! I had a laparoscopoy done about 8 years ago to get rid of some and i did not know they could come back!! But they did, with a vengeance. So, Endovan has given me hope! I will keep everyone updated on progress. Also, the customer service has been great!